SALIVARY MICROBIOME MODULATION BY DIGITAL ORTHODONTIC WORKFLOWS

Abstract

The rapid incorporation of digital workflows in orthodontics has transformed diagnosis, treatment planning, and appliance fabrication. Beyond mechanical efficiency and esthetic predictability, emerging evidence suggests that digital orthodontic approaches may influence the oral ecosystem, particularly the salivary microbiome. This narrative literature review explores how digital orthodontic workflows—such as intraoral scanning, computer-aided design and manufacturing (CAD/CAM), customized aligners, and reduced chair-time protocols—may indirectly modulate salivary microbial balance. Databases were searched for studies addressing orthodontic digitalization, oral microbiome dynamics, salivary biomarkers, and periodontal outcomes. Findings suggest that digitally planned treatments can reduce plaque-retentive surfaces, minimize iatrogenic trauma, and shorten treatment duration, factors associated with more stable microbial profiles. Although direct evidence remains limited, the interaction between digital orthodontics and salivary microbiome homeostasis represents an innovative field with potential implications for caries risk, periodontal health, and long-term oral stability.